I may be a bit of a hoarder. I keep at least 1 of every Any Hero unique at all times. However, when they stop dropping I'll have less incentive to keep them. So my question to you, is what items will you keep period. I'm talking about items from comic runs you enjoyed, or maybe ones that were so hard to get that there is no way you would ever get rid of them.
For me there's
Hannibal King's Handcannon - All Midnight Sons related paraphernalia must be kept
The Darkhold - It took me FOREVER to find one and also see above
Mechanical Arms of Doc OCk - It makes giggle to remember having these on Punisher and then wishing they also had a visual effect
There's more, but those three are ones the Gaz is going to have to pry from my cold dead hands.