So Mr. Hyde breaks out of prison, bringing with him the Lizard. He attacks the Bronx zoo and has the Lizard's... um, lizards... fight you to slow you down.
And then Kraven the Hunter.
Why? What's he doing there? Does he just hang out in the zoo all day trying to hide from zookeepers while hunting the animals? And then he sees you coming and is like "Eh, I'll fight this person, I was bored anyway."? What's his deal?